AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of PRKAG2 in mouse heart lysates using PRKAG2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human gastric cancer using AMPK gamma 2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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