This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Human bladder Carcinoma using GLI1 antibbody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using GLI1 antibbody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.