L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones; inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis; suppresses the delayed type hypersensitivity response; stimulates Th2 cell response (which results in elevated antibody production); and promotes mast cell proliferation in combination with IL-4.

推荐稀释比 FC:5μL per test for million cells or whole blood in 100 μL volume.

Flow Cytometry analysis of HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding mouse IL-10 gene stained with (APC) IL-10 antibody (filled gray histogram) or (APC) rat IgG2b, κ lsoty(PE) Control (empty black histogram).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。