Recombinant Mouse SIRP-α/CD172A Protein,hFc Tag
产品介绍
Signal regulatory protein alpha (SIRP alpha, designated CD172a), also called SHPS-1 (SHP substrate 1) and previously, MyD-1 (Myeloid/Dendritic-1), is a monomeric ~90 kDa type I transmembrane glycoprotein that belongs to the SIRP/SHPS (CD172) family of the immunoglobulin superfamily . SIRPs are paired receptors, with similar extracellular domains but differing C-termini and functions . The 503 amino acid (aa) human SIRP alpha contains a 342 aa extracellular domain (ECD), with one V-type, and two C1 type Ig domains, and three potential N glycosylation sites
产品性质
产品特色
高活性、高纯度、低内毒素、高批间一致性
应用案例
ELISA Data: Immobilized CD47 His Tag,Mouse at 2.0μg/mL (100μL/well) can bind SIRP-α/CD172A Fc Chimera,Mouse with EC50 of 27.10-36.13ng/mL .
SPR Data：Protein A Chip captured Mouse SIRP-α/CD172A Fc Chimera can bind Mouse CD47 His Tag,with an affinity constant of 1.56μM as determined in SPR assay.
存储条件
-25 ~ -15℃保存，收到货之后有效期1年。复溶后，无菌条件下，2~8℃保存，7天有效期。复溶后， 无菌条件下，-85 ~ -65℃保存，3个月有效期。
COA
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