BML-284 (Wnt agonist 1, AMBMP, BML284)，又称CID11210285盐酸盐，是一种具有细胞通透性的选择性Wnt信号激活剂，能诱导TCF介导的转录活性(EC₅₀ > 700 nM)。BML-284激活Wnt但不抑制GSK-3β。

参考文献

[1].Liu J, et al. A small-molecule agonist of the Wnt signaling pathway. Angew Chem Int Ed Engl. 2005 Mar 18;44(13):1987-90.

[2].Ying Jiang, et al. Pizotifen inhibits the proliferation and invasion of gastric cancer cells. Exp Ther Med. 2020 Feb;19(2):817-824.

[3].Yunlong Meng, et al. Exposure to pyrimethanil induces developmental toxicity and cardiotoxicity in zebrafish. Chemosphere. 2020 Sep;255:126889.

冰袋运输。粉末直接保存于-25~-15℃，有效期3年。建议干燥保存，避免反复冻融。