Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2.

稀释比 IF: 1/50-200 WB: 1/500-1/2000 IHC-p: 1/100-1/300 ELISA: 1/20000

冰袋运输。-20℃保存。