Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55.

稀释比 WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 FC: 1/50

冰袋运输。-20℃保存。