Cidofovir (GS 0504, GS0504, HPMPC, (S)-HPMPC) dihydrate，又称西多福韦二水合物或昔多呋韦二水合物，是一种无环单磷酸核苷酸类似物，一种可注射的抗病毒药。Cidofovir可通过抑制病毒DNA的合成来抑制巨细胞病毒(CMV)复制，是抗CMV新药。Cidofovir对其它病毒感染，如正痘病毒、天花病毒、单纯疱疹病毒等。

参考文献

[1].David J Maggs, et al. In vitro efficacy of ganciclovir, cidofovir, penciclovir, foscarnet, idoxuridine, and acyclovir against feline herpesvirus type-1. Am J Vet Res. 2004 Apr;65(4):399-403.

[2].M Bray, et al. Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challenge. J Infect Dis. 2000 Jan;181(1):10-9.

[3].Simona Catalani, et al. Reduced cell viability and apoptosis induction in human thyroid carcinoma and mesothelioma cells exposed to cidofovir. Toxicol In Vitro. 2017 Jun;41:49-55.

[4].Robert O Baker, et al. Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections. Antiviral Res. 2003 Jan;57(1-2):13-23.

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