Carboplatin (NSC 241240, NSC241240, CBDCA, JM-8)，又称卡铂或碳铂，是顺铂的衍生物，是一种DNA合成抑制剂，与DNA 结合，抑制复制，并干扰其修复机制。
-25～-15℃保存，有效期3年。建议分装后-25～-15℃干燥保存，避免反复冻融。
[1] Natarajan G, et al. Increased DNA-binding activity of cis-1,1-cyclobutanedicarboxylatodiammineplatinum(II) (carboplatin) in the presence of nucleophiles and human breast cancer MCF-7 cell cytoplasmic extracts: activation theory revisited. Biochem Pharmacol. 1999 Nov 15;58(10):1625-9.
[2] Banerji U, et al. An in vitro and in vivo study of the combination of the heat shock protein inhibitor 17-allylamino-17-demethoxygeldanamycin and carboplatin in human ovarian cancer models. Cancer Chemother Pharmacol. 2008 Oct;62(5):769-78.
[3] Clark CC, et al. Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models. Mol Cancer Ther. 2012 Sep;11(9):1948-58.
