Medroxyprogesterone Acetate是广泛应用的合成类固醇，作为人体孕激素的人工合成类似物，既是强效孕激素受体激动剂，也可与雄激素受体及糖皮质激素受体结合。
| 英文别名 (English Synonym) | Medroxyprogesterone Acetate |
| 中文名称 (Chinese Name) | 醋酸甲羟孕酮 |
| 靶点 (Target) | Estrogen/progestogen Receptor |
| 通路 (Pathway) | Endocrinology and Hormones |
| CAS号 (CAS NO.) | 71-58-9 |
| 分子式 (Formula) | C24H34O4 |
| 分子量 (Molecular Weight) | 386.52 |
| 纯度 (Purity) | ≥98% |
| 溶解性 (Solubility) | 溶于DMSO |
-25~-15℃保存，有效期3年
[1] Simoncini T, Mannella P, Fornari L, Caruso A, Willis MY, Garibaldi S, Baldacci C, Genazzani AR. Differential signal transduction of progesterone and medroxyprogesterone acetate in human endothelial cells. Endocrinology. 2004 Dec;145(12):5745-56. doi: 10.1210/en.2004-0510. Epub 2004 Sep 9. PMID: 15358673.[2]Smith D, Enever R, Dey M, Latta D, Weierstall R. Pharmacokinetics and bioavailability of medroxyprogesterone acetate in the dog and the rat. Biopharm Drug Dispos. 1993 May;14(4):341-55. doi: 10.1002/bdd.2510140407. PMID: 8499584.[3]Bernardi F, Pluchino N, Pieri M, Begliuomini S, Lenzi E, Puccetti S, Casarosa E, Luisi M, Genazzani AR. Progesterone and medroxyprogesterone acetate effects on central and peripheral allopregnanolone and beta-endorphin levels. Neuroendocrinology. 2006;83(5-6):348-59. doi: 10.1159/000095400. Epub 2006 Aug 24. PMID: 16931878.
