This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Human pancreas tissue using GBA antibbody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human liver Carcinoma using GBA antibbody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.