Glycyrrhizic acid，又称甘草酸，是甘草中最主要的活性成分，为三萜皂甙，是HMGB1抑制剂，具有抗炎、抗病毒和抗肿瘤活性，临床上已被用于治疗慢性肝炎，也可作为食品的甜味剂。

参考文献

[1] Hingorani P, Zhang W, Piperdi S, et al. Preclinical activity of palifosfamide lysine (ZIO-201) in pediatric sarcomas including oxazaphosphorine-resistant osteosarcoma. Cancer Chemother Pharmacol. 2009 Sep;64(4):733-40. doi: 10.1007/s00280-008-0922-4(IF:3.008).

[2] Wang LY, Cheng KC, Li Y, et al. Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats. Biomed Pharmacother. 2017 Nov;95:599-604. doi: 10.1016/j.biopha.2017.08.087(IF:3.743).

[3] Li C, Peng S, Liu X, et al. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid. 2017 May;27(5):722-731. doi: 10.1089/thy.2016.0432(IF:7.786).

-25~-15℃保存，有效期3年。