Acetazolamide是一种碳酸酐酶（CA）IX抑制剂,具有利尿、抗高血压和抗淋球菌活性。
|
英文别名 (English Synonym) |
Acetazolamide |
|
中文名称 (Chinese Name) |
乙酰唑胺 |
|
靶点 (Target) |
Carbonic Anhydrase |
|
通路 (Pathway) |
Protease/Metabolic Enzyme |
|
CAS号 (CAS NO.) |
59-66-5 |
|
分子式 (Formula) |
C4H6N4O3S2 |
|
分子量 (Molecular Weight) |
222.25 |
|
纯度 (Purity) |
≥98% |
|
溶解性 (Solubility) |
溶于DMSO |
-25~-15℃保存，有效期3年
[1] Bayat Mokhtari R, Baluch N, Ka Hon Tsui M, Kumar S, S Homayouni T, Aitken K, Das B, Baruchel S, Yeger H. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma. BMC Cancer. 2017 Feb 24,17(1):156. doi: 10.1186/s12885-017-3126-7. PMID: 28235409, PMCID: PMC5326494.[2]Gao H, Dong H, Li G, Jin H. Combined treatment with acetazolamide and cisplatin enhances chemosensitivity in laryngeal carcinoma Hep-2 cells. Oncol Lett. 2018 Jun,15(6):9299-9306. doi: 10.3892/ol.2018.8529. Epub 2018 Apr 18. PMID: 29928333, PMCID: PMC6004654.
